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Trials
A Phase I/II Study of HYP-6589 Monotherapy in Treating Advanced Solid Tumors and in Combination With Tyrosine Kinase Inhibitors in Treating Patients With Advanced NSCLC Positive for Driver Genes

trialsTrialRecruiting

A Phase I/II Study of HYP-6589 Monotherapy in Treating Advanced Solid Tumors and in Combination With Tyrosine Kinase Inhibitors in Treating Patients With Advanced NSCLC Positive for Driver Genes

A phase 1/2 trial of Test Product HYP-6589 in advanced solid tumours, run by Sichuan Huiyu Pharmaceutical Co., Ltd, now recruiting.

Overview Connected2

Overview

A Phase I/II Study of HYP-6589 Monotherapy in Treating Advanced Solid Tumors and in Combination With Tyrosine Kinase Inhibitors in Treating Patients With Advanced NSCLC Positive for Driver Genes is a phase 1/2 interventional study registered as NCT06712680 by Sichuan Huiyu Pharmaceutical Co., Ltd, with 115 participants planned, started 2024-11-27 and due to reach its primary completion in 2028-04-10. Interventions recorded: Test Product HYP-6589.

Setting

A Phase I/II , Open-label, Multi-center, Multi-cohort Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of HYP-6589 Monotherapy in Advanced Solid Tumors and Combination With Tyrosine Kinase Inhibitors in Patients With Advanced NSCLC With Target-driven Gene Positivity

Phase

Phase 1/2

Sponsor

Sichuan Huiyu Pharmaceutical Co., Ltd

Registry

Started

2024-11-27

Enrolled

115 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Sichuan Huiyu Pharmaceutical

Evidence strength18/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
115 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Orphan trials · diff · file

Sources & links

ClinicalTrials.gov NCT06712680

Data

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