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Trials
A Trial of HRS-2189 in Combination With Fluvastatin±HRS-6209, or HRS-8080±HRS-6209, or HRS-6209+HRS-1358 in Breast Cancer Patients

trialsTrialRecruiting

A Trial of HRS-2189 in Combination With Fluvastatin±HRS-6209, or HRS-8080±HRS-6209, or HRS-6209+HRS-1358 in Breast Cancer Patients

A phase 1/2 trial of HRS-8080 in advanced solid tumours, run by Shandong Suncadia Medicine Co., Ltd., now recruiting.

Overview Connected3

Overview

A Trial of HRS-2189 in Combination With Fluvastatin±HRS-6209, or HRS-8080±HRS-6209, or HRS-6209+HRS-1358 in Breast Cancer Patients is a phase 1/2 interventional study registered as NCT06679036 by Shandong Suncadia Medicine Co., Ltd., with 300 participants planned, started 2025-01-21 and due to reach its primary completion in 2026-10-30. Interventions recorded: HRS-2189, Fluvustat, HRS-8080, HRS-6209 and HRS-1358.

Setting

An Open, Multicenter Phase Ib/II Clinical Study on the Safety, Tolerance, Pharmacokinetics, and Initial Efficacy of HRS-2189 in Combination With Fluvastatin±HRS-6209, or HRS-8080±HRS-6209, or HRS-6209+HRS-1358 in Patients With Advanced Unresectable or Metastatic Breast Cancer

Phase

Phase 1/2

Sponsor

Shandong Suncadia Medicine Co., Ltd.

Registry

Started

2025-01-21

Enrolled

300 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

Phase 3small molecule (structure undisclosed or not yet in PubChem)

companies

Jiangsu Hengrui Pharmaceuticals

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
300 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06679036

Data

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Cancers

Metastatic cancer (cancer that has spread)

Products

HRS-8080

Companies

Jiangsu Hengrui Pharmaceuticals

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Model panel commentary is coming to this page: machine commentary, not clinical review.

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