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Trials
A Study of AP402 in HER2-Positive Patients With Locally or Advanced Solid Tumors

trialsTrialRecruiting

A Study of AP402 in HER2-Positive Patients With Locally or Advanced Solid Tumors

A phase 1/2 trial of AP402 (Part 1 Dose esclation) in advanced solid tumours, run by AP Biosciences Inc., now recruiting.

Overview Connected2

Overview

A Study of AP402 in HER2-Positive Patients With Locally or Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06669975 by AP Biosciences Inc., with 85 participants planned, started 2025-04-22 and due to reach its primary completion in 2026-12-01. Interventions recorded: AP402 (Part 1 Dose esclation) and AP402 (Part 2 Dose Expansion).

Setting

A Phase 1/2, Open-label Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Activity of AP402 in HER2-Positive Patients With Locally or Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

AP Biosciences Inc.

Registry

Started

2025-04-22

Enrolled

85 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Evidence strength18/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
85 enrolled+10
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06669975

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

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AP Biosciences

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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id nct06669975.

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