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Trials
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

trialsTrialRecruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

A phase 1/2 trial of TUB-030 in small-cell lung cancer, non-small-cell lung cancer and triple-negative breast cancer, run by Tubulis GmbH, now recruiting.

Overview Connected4

Overview

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06657222 by Tubulis GmbH, with 250 participants planned, started 2024-12-13 and due to reach its primary completion in 2028-12. Interventions recorded: TUB-030.

Setting

A Multicenter FIH Dose Escalation and Optimization Phase I/IIa Trial to Investigate Safety, Tolerability, PK, and Efficacy of the 5T4 ADC TUB-030 in Patients With Advanced Solid Tumors (5-STAR 1-01)

Phase

Phase 1/2

Sponsor

Tubulis GmbH

Registry

Started

2024-12-13

Enrolled

250 enrolled

Connected

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cancers

Non-small-cell lung cancer Small-cell lung cancer Triple-negative breast cancer (TNBC)

companies

Tubulis (Gilead)

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
250 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT06657222

Data

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Cancers

Small-cell lung cancer
Non-small-cell lung cancer
Triple-negative breast cancer (TNBC)

Companies

Tubulis (Gilead)

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