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Trials
Safety and Efficacy Study of Zamtocabtagene Autoleucel (MB-CART2019.1) in Pediatric Patients With R/R B-Cell Neoplasms

trialsTrialRecruiting

Safety and Efficacy Study of Zamtocabtagene Autoleucel (MB-CART2019.1) in Pediatric Patients With R/R B-Cell Neoplasms

A phase 2 trial of Zamtocabtagene autoleucel in advanced solid tumours, run by Miltenyi Biomedicine GmbH, now recruiting.

Also called: DALY PED

Overview Connected3

Overview

Safety and Efficacy Study of Zamtocabtagene Autoleucel (MB-CART2019.1) in Pediatric Patients With R/R B-Cell Neoplasms is a phase 2 interventional study registered as NCT06508931 by Miltenyi Biomedicine GmbH, with 31 participants planned, started 2025-08-04 and due to reach its primary completion in 2029-12-31. Interventions recorded: zamtocabtagene autoleucel (MB-CART2019.1).

Setting

A Single-arm, Multi-center, Open-label Phase II Study to Determine the Safety and Efficacy of MB-CART2019.1 in Pediatric Subjects With Relapsed/Refractory Mature B-cell Neoplasms Who Have Relapsed After One or More Prior Therapies, Including Subjects With Primary Refractory Disease

Phase

Phase 2

Sponsor

Miltenyi Biomedicine GmbH

Registry

Started

2025-08-04

Enrolled

31 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

Phase 2CAR-T cell therapy

Zamtocabtagene autoleucel

companies

Miltenyi Biomedicine

Evidence strength22/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
31 enrolled+7
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · A further 160 trial acronyms added as aliases to registry… · diff · file

Sources & links

ClinicalTrials.gov NCT06508931

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

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Zamtocabtagene autoleucel

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Miltenyi Biomedicine

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