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Trials
Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

trialsTrialRecruiting

Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

A phase 1/2 trial of ISM3412 in advanced solid tumours, run by InSilico Medicine Hong Kong Limited, now recruiting.

Overview Connected2

Overview

Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors is a phase 1/2 interventional study registered as NCT06414460 by InSilico Medicine Hong Kong Limited, with 146 participants planned, started 2025-04-25 and due to reach its primary completion in 2028-03-31. Interventions recorded: ISM3412.

Setting

A Phase 1/2, Open-Label, Multicenter, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics/Pharmacodynamics, and Preliminary Efficacy of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

Phase

Phase 1/2

Sponsor

InSilico Medicine Hong Kong Limited

Registry

Started

2025-04-25

Enrolled

146 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Insilico Medicine

Evidence strength19/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
146 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Orphan trials · diff · file

Sources & links

ClinicalTrials.gov NCT06414460

Data

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