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Trials
PTT-936 Alone or in Combination in Patients With Locally Advanced or Metastatic Solid Tumors

trialsTrialRecruiting

PTT-936 Alone or in Combination in Patients With Locally Advanced or Metastatic Solid Tumors

A phase 1/2 trial of PTT-936 in advanced solid tumours, run by Pyrotech Therapeutics, Inc., now recruiting.

Overview Connected2

Overview

PTT-936 Alone or in Combination in Patients With Locally Advanced or Metastatic Solid Tumors is a phase 1/2 interventional study registered as NCT06244992 by Pyrotech Therapeutics, Inc., with 68 participants planned, started 2024-01-26 and due to reach its primary completion in 2027-09-30. Interventions recorded: PTT-936 and Combination of PTT-936 and anti-PD-1/L1 therapy.

Setting

A Phase 1/2a Study to Evaluate the Safety, Pharmacokinetics and Efficacy of PTT-936, an Alpha Kinase 1 (ALPK1) Activator, Alone or in Combination With Anti-PD-1/L1 in Patients With Locally Advanced or Metastatic Solid Tumors

Phase

Phase 1/2

Sponsor

Pyrotech Therapeutics, Inc.

Registry

Started

2024-01-26

Enrolled

68 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

targets

Evidence strength17/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
68 enrolled+9
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Backlink fill · diff · file

Sources & links

ClinicalTrials.gov NCT06244992

Data

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