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Trials
A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Cervical Cancer and Other Gynecological Malignancies

trialsTrialRecruiting

A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Cervical Cancer and Other Gynecological Malignancies

A phase 2 trial of Izalontamab brengitecan in cervical cancer, run by Sichuan Baili Pharmaceutical Co., Ltd., now recruiting.

Overview Connected6

Overview

A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Recurrent or Metastatic Cervical Cancer and Other Gynecological Malignancies is a phase 2 interventional study registered as NCT05990803 by Sichuan Baili Pharmaceutical Co., Ltd., with 130 participants planned, started 2023-11-06 and due to reach its primary completion in 2026-12. Interventions recorded: BL-B01D1, SI-B003. Conditions listed: Cervical Cancer. No results are recorded here; the registry entry is the source.

Setting

A Phase II Clinical Study to Evaluate the Efficacy and Safety of BL-B01D1 Monotherapy, SI-B003 Monotherapy and BL-B01D1+SI-B003 Combination Therapy (BL-B01D1+SI-B003) in Patients With Recurrent or Metastatic Cervical Cancer and Other Gynecological Malignancies

Phase

Phase 2

Sponsor

Sichuan Baili Pharmaceutical Co., Ltd.

Registry

Started

2023-11-06

Enrolled

130 enrolled

Connected

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cancers

Cervical cancer Recurrent or metastatic cervical cancer

technologies

Antibody-drug conjugate (ADC)Bispecific ADC

drugs

Phase 3Bispecific ADC

Izalontamab brengitecan

companies

SystImmune / Sichuan Biokin

Evidence strength26/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
130 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT05990803

Data

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Cancers

Cervical cancer
Recurrent or metastatic cervical cancer

Technologies

Antibody-drug conjugate (ADC)
Bispecific ADC

Products

Izalontamab brengitecan

Companies

SystImmune / Sichuan Biokin

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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