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Trials
BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants

trialsTrialActive

BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants

A phase 3 trial of Durvalumab in bladder & urothelial cancer, run by AstraZeneca, active and no longer recruiting.

Also called: PATAPSCO

Overview Connected6

Overview

BCG in Combination With Durvalumab in Adult BCG-naïve, High-risk NMIBC Participants is a phase 3 interventional study registered as NCT05943106 by AstraZeneca, with 100 participants enrolled, started 2023-08-11 and due to reach its primary completion in 2025-06-16. Interventions recorded: Durvalumab and BCG.

Setting

A Phase IIIb Open-Label, Single-Arm, Multi-Center, US Study of Bacillus Calmette-Guerin (BCG) Administered in Combination With Durvalumab in Adult BCG-naïve, High-risk Non-Muscle- Invasive Bladder Cancer Participants (PATAPSCO)

Phase

Phase 3

Sponsor

AstraZeneca

Registry

Started

2023-08-11

Enrolled

100 enrolled

Connected

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cancers

Bladder & urothelial cancer Non-muscle-invasive bladder cancer

technologies

Immune checkpoint inhibitors

drugs

ApprovedMonoclonal antibody (anti-PD-L1)

Durvalumab · Imfinzi

companies

AstraZeneca Parexel

Evidence strength45/100 · Emerging

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 3+30
100 enrolled+10
No structured primary endpoint0
Result: active0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT05943106

Data

JSON ·

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Cancers

Bladder & urothelial cancer
Non-muscle-invasive bladder cancer

Technologies

Immune checkpoint inhibitors

Products

Durvalumab

Companies

AstraZeneca
Parexel

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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