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A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)

trialsTrialActive

A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)

A phase 1/2 trial of BEAM-201 in non-Hodgkin lymphoma, run by Beam Therapeutics Inc., active and no longer recruiting.

Also called: BEAM-201

Overview Connected2

Overview

A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL) is a phase 1/2 interventional study registered as NCT05885464 by Beam Therapeutics Inc., with 5 participants enrolled, started 2023-05-25 and due to reach its primary completion in 2026-12. Interventions recorded: BEAM-201.

Setting

A Phase 1/2, Dose-Exploration and Dose-Expansion Study Evaluating the Safety and Efficacy of Multiplex Base-Edited, Allogeneic Anti-CD7 CAR-T Cells (BEAM-201) in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)

Phase

Phase 1/2

Sponsor

Beam Therapeutics Inc.

Registry

Started

2023-05-25

Enrolled

5 enrolled

Connected

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cancers

Non-Hodgkin lymphoma (all types)

targets

Evidence strength11/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
5 enrolled+3
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Trial acronyms for registry records · diff · file

Sources & links

ClinicalTrials.gov NCT05885464

Data

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Cancers

Non-Hodgkin lymphoma (all types)

Targets

CD7

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