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Trials
A Study of PM8002 in Combination With Chemotherapy in Patients With NEN

trialsTrialActive

A Study of PM8002 in Combination With Chemotherapy in Patients With NEN

A phase 2 trial of PM8002 in neuroendocrine tumours, run by Biotheus Inc., active and no longer recruiting.

Overview Connected3

Overview

A Study of PM8002 in Combination With Chemotherapy in Patients With NEN is a phase 2 interventional study registered as NCT05879055 by Biotheus Inc., with 31 participants enrolled, started 2023-05-17 and due to reach its primary completion in 2027-01-01. Interventions recorded: PM8002 and FOLFIRI.

Setting

A Phase II Study to Evaluate the Efficacy, Safety and Pharmacokinetics of PM8002 Injection in Combination With Chemotherapy as Second Line Therapy in Unresectable Neuroendocrine Neoplasm

Phase

Phase 2

Sponsor

Biotheus Inc.

Registry

Started

2023-05-17

Enrolled

31 enrolled

Connected

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cancers

Neuroendocrine tumours

drugs

Phase 3bispecific antibody

companies

Evidence strength22/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
31 enrolled+7
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT05879055

Data

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Cancers

Neuroendocrine tumours

Products

PM8002

Companies

BioNTech

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id nct05879055.

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