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Trials
TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3)

trialsTrialActive

TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3)

A phase 1/2 trial of TAC01-CLDN18.2 in advanced solid tumours, run by Triumvira Immunologics, Inc., active and no longer recruiting.

Also called: TACTIC-3

Overview Connected4

Overview

TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3) is a phase 1/2 interventional study registered as NCT05862324 by Triumvira Immunologics, Inc., with 113 participants enrolled, started 2023-08-23 and due to reach its primary completion in 2027-08-01. Interventions recorded: TAC01-CLDN18.2.

Setting

A Phase 1/2 Study Investigating the Safety and Efficacy of Autologous TAC T Cells in Subjects With Unresectable, Locally Advanced or Metastatic Claudin 18.2+ Solid Tumors

Phase

Phase 1/2

Sponsor

Triumvira Immunologics, Inc.

Registry

Started

2023-08-23

Enrolled

113 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

technologies

TCR-T cell therapy

drugs

Phase 2TCR-T cell therapy

companies

Triumvira Immunologics

Evidence strength18/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
113 enrolled+10
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT05862324

Data

JSON ·

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Cancers

Metastatic cancer (cancer that has spread)

Technologies

TCR-T cell therapy

Products

TAC01-CLDN18.2

Companies

Triumvira Immunologics

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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