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Trials
LYL273 for Patients With Relapsed or Refractory mCRC

trialsTrialRecruiting

LYL273 for Patients With Relapsed or Refractory mCRC

A phase 1/2 trial of LYL273 in colorectal cancer, run by Lyell Immunopharma, Inc., now recruiting.

Also called: CARABiNER

Overview Connected2

Overview

LYL273 for Patients With Relapsed or Refractory mCRC is a phase 1/2 interventional study registered as NCT05319314 by Lyell Immunopharma, Inc., with 155 participants planned, started 2022-08-01 and due to reach its primary completion in 2028-06. Interventions recorded: LYL273.

Setting

A Phase 1/2 Multicenter Study Evaluating the Safety and Efficacy of LYL273 in Patients With Relapsed or Refractory Metastatic Colorectal Cancer

Phase

Phase 1/2

Sponsor

Lyell Immunopharma, Inc.

Registry

Started

2022-08-01

Enrolled

155 enrolled

Connected

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cancers

Colorectal cancer

companies

Lyell Immunopharma

Evidence strength19/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
155 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · A further 160 trial acronyms added as aliases to registry… · diff · file

Sources & links

ClinicalTrials.gov NCT05319314

Data

JSON ·

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Cancers

Colorectal cancer

Companies

Lyell Immunopharma

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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