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Trials
Safety and Efficacy of APG-157 in Head and Neck Cancer

trialsTrialActive

Safety and Efficacy of APG-157 in Head and Neck Cancer

A phase 2 trial of APG-157 in head and neck squamous cell carcinoma, run by Aveta Biomics, Inc., active and no longer recruiting.

Overview Connected4

Overview

Safety and Efficacy of APG-157 in Head and Neck Cancer is a phase 2 interventional study registered as NCT05312710 by Aveta Biomics, Inc., with 24 participants enrolled, started 2022-04-22 and due to reach its primary completion in 2026-12. Interventions recorded: APG-157.

Setting

Phase 2 Study to Evaluate the Safety and Efficacy of APG-157 as Neoadjuvant/Induction Therapy for Patients With Head and Neck Squamous Cell Cancer (HNSCC) of the Oral Cavity and/or Oropharynx

Phase

Phase 2

Sponsor

Aveta Biomics, Inc.

Registry

Started

2022-04-22

Enrolled

24 enrolled

Connected

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cancers

Head and neck squamous cell carcinoma Oral cavity cancer (mouth and tongue)Oropharyngeal cancer (tonsil and base of tongue)

companies

Evidence strength22/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 2+15
24 enrolled+7
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link 1,018 registry trials to cancer subtype pages by dri… · diff · file

Sources & links

ClinicalTrials.gov NCT05312710

Data

JSON ·

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Cancers

Head and neck squamous cell carcinoma
Oral cavity cancer (mouth and tongue)
Oropharyngeal cancer (tonsil and base of tongue)

Companies

Aveta Biomics

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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MCP server: npx -y onco-mcp, tools search, get_entity, list_kind, ask, context, compare. This record is get_entity or context with id nct05312710.

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