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Trials
Phase 1/2 Study of TU2218 Alone and in Combination With Checkpoint Inhibitors in Patients With Advanced Solid Tumors

trialsTrialRecruiting

Phase 1/2 Study of TU2218 Alone and in Combination With Checkpoint Inhibitors in Patients With Advanced Solid Tumors

A phase 1/2 trial of TU2218 in advanced solid tumours, run by TiumBio Co., Ltd., now recruiting.

Overview Connected2

Overview

Phase 1/2 Study of TU2218 Alone and in Combination With Checkpoint Inhibitors in Patients With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT05204862 by TiumBio Co., Ltd., with 240 participants planned, started 2021-12-02 and due to reach its primary completion in 2026-06-30. Interventions recorded: TU2218 and Anti-PD-1 antibody.

Setting

A Phase 1/2 Study to Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TU2218, an Oral TGFβR Inhibitor, Administered Alone and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Phase

Phase 1/2

Sponsor

TiumBio Co., Ltd.

Registry

Started

2021-12-02

Enrolled

240 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

companies

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
240 enrolled+12
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT05204862

Data

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