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Trials
Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX or Irinotecan in Patients With Advanced Gastric Cancer

trialsTrialActive

Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX or Irinotecan in Patients With Advanced Gastric Cancer

A phase 1/2 trial of IDX-1197+XELOX in gastric & gastro-oesophageal junction cancer, run by Idience Co., Ltd., active and no longer recruiting.

Overview Connected7

Overview

Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX or Irinotecan in Patients With Advanced Gastric Cancer is a phase 1/2 interventional study registered as NCT04725994 by Idience Co., Ltd., with 87 participants enrolled, started 2021-06-28 and due to reach its primary completion in 2026-07-31. Interventions recorded: IDX-1197+XELOX and IDX-1197+Irinotecan.

Setting

An Open-Label, International, Multicenter, Phase 1b/2a Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX (Capecitabine and Oxaliplatin) or Irinotecan in Patients With Advanced Gastric Cancer

Phase

Phase 1/2

Sponsor

Idience Co., Ltd.

Registry

Started

2021-06-28

Enrolled

87 enrolled

Connected

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cancers

Gastric & gastro-oesophageal junction cancer

technologies

Cytotoxic chemotherapy Platinum agents

drugs

ApprovedOral fluoropyrimidine prodrug (antimetabolite)

Capecitabine · Xeloda

ApprovedCytotoxic regimen

CAPOX (capecitabine, oxaliplatin)

ApprovedTopoisomerase I inhibitor (camptothecin prodrug)

Irinotecan (and liposomal irinotecan) · Camptosar / Onivyde

ApprovedThird-generation platinum (DACH-platinum)

Oxaliplatin · Eloxatin

Evidence strength23/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
87 enrolled+10
No structured primary endpoint0
Result: active0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-22 · Jude Gomila · Wave 2 corpus-only joins applied · diff · file

Sources & links

ClinicalTrials.gov NCT04725994

Data

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Cancers

Gastric & gastro-oesophageal junction cancer

Technologies

Cytotoxic chemotherapy
Platinum agents

Products

CAPOX (capecitabine, oxaliplatin)
Oxaliplatin
Irinotecan (and liposomal irinotecan)
Capecitabine

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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