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Trials
Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

trialsTrialRecruiting

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

A phase 1/2 trial of Osimertinib, Pemetrexed, Carboplatin in mesothelioma, run by Vivace Therapeutics, Inc, now recruiting.

Overview Connected4

Overview

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors is a phase 1/2 interventional study registered as NCT04665206 by Vivace Therapeutics, Inc, with 434 participants planned, started 2021-03-24 and due to reach its primary completion in 2029-11-02. Interventions recorded: VT3989, Nivolumab & Ipilimumab, Osimertinib, Pemetrexed/Carboplatin. Conditions listed: Solid Tumor, Adult, Mesothelioma, NSCLC. No results are recorded here; the registry entry is the source.

Setting

Phase I/II, Multi-Center, Open-Label Study of VT3989, Alone or in Combination, in Patients With Locally Advanced or Metastatic Solid Tumors

Phase

Phase 1/2

Sponsor

Vivace Therapeutics, Inc

Registry

Started

2021-03-24

Enrolled

434 enrolled

Connected

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MAPS
Shares Mesothelioma, Pemetrexed.

cancers

drugs

ApprovedCytotoxic chemotherapy (platinum)

ApprovedSmall-molecule kinase inhibitor (EGFR)

Osimertinib · Tagrisso

ApprovedCytotoxic (antifolate)

Pemetrexed · Alimta (and generics)

Evidence strength26/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
434 enrolled+13
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Header signup, trial wave 5 and Ask weighting · diff · file

Sources & links

ClinicalTrials.gov NCT04665206

Data

JSON ·

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Cancers

Mesothelioma

Products

Osimertinib
Pemetrexed
Carboplatin

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