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Trials
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

trialsTrialRecruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

A phase 1/2 trial of Prednisone, Dexamethasone and Lenvatinib in advanced solid tumours, run by Eisai Inc., now recruiting.

Overview Connected6

Overview

A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types is a phase 1/2 interventional study registered as NCT04300556 by Eisai Inc., with 182 participants planned, started 2020-08-06 and due to reach its primary completion in 2030-08-08. Interventions recorded: Farletuzumab ecteribulin, Prednisone, Prednisolone, Dexamethasone and Lenvatinib.

Setting

A Multicenter, Open-Label Phase 1/2 Trial Evaluating the Safety, Tolerability, and Efficacy of MORAb-202, a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Subjects With Selected Tumor Types

Phase

Phase 1/2

Sponsor

Eisai Inc.

Registry

Started

2020-08-06

Enrolled

182 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

ApprovedGlucocorticoid

Dexamethasone · Decadron (historic) / Hemady / Neofordex

Phase 2Antibody-drug conjugate

Farletuzumab ecteribulin

ApprovedSmall-molecule multi-kinase inhibitor (VEGFR, FGFR, PDGFR, RET, KIT)

Lenvatinib · Lenvima

ApprovedGlucocorticoid

Prednisone · Deltasone (historic) / Rayos

companies

Evidence strength24/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
182 enrolled+11
No structured primary endpoint0
Result: recruiting0
No independent replication recorded0
A linked product is approved+5

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-17 · Jude Gomila · Reverse links for orphaned drugs and companies · diff · file

Sources & links

ClinicalTrials.gov NCT04300556

Data

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Cancers

Metastatic cancer (cancer that has spread)

Products

Prednisone
Dexamethasone
Lenvatinib
Farletuzumab ecteribulin

Companies

Eisai

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

Model panel commentary is coming to this page: machine commentary, not clinical review.

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