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Trials
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Participants With Advanced Cancers

trialsTrialActive

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Participants With Advanced Cancers

A phase 1/2 trial of Cetrelimab in advanced solid tumours, run by Janssen Research & Development, LLC, active and no longer recruiting.

Overview Connected3

Overview

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Participants With Advanced Cancers is a phase 1/2 interventional study registered as NCT02908906 by Janssen Research & Development, LLC, with 234 participants enrolled, started 2016-11-21 and due to reach its primary completion in 2023-11-17. Interventions recorded: JNJ-63723283.

Setting

63723283LUC1001: A First-in-Human, Open-label, Phase 1/2 Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Subjects With Advanced Cancers

Phase

Phase 1/2

Sponsor

Janssen Research & Development, LLC

Registry

Started

2016-11-21

Enrolled

234 enrolled

Connected

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cancers

Metastatic cancer (cancer that has spread)

drugs

Phase 3antibody (INN stem -mab; form not stated in the registry record)

companies

Johnson & Johnson

Evidence strength20/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
234 enrolled+12
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-16 · Jude Gomila · Registry trials wave 6 and products wave 7 · diff · file

Sources & links

ClinicalTrials.gov NCT02908906

Data

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Cancers

Metastatic cancer (cancer that has spread)

Products

Cetrelimab

Companies

Johnson & Johnson

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Model panel commentary is coming to this page: machine commentary, not clinical review.

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