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Trials
Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma

trialsTrialActive

Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma

A phase 1/2 trial of Perillyl alcohol in glioma & glioblastoma, run by Neonc Technologies, Inc., active and no longer recruiting.

Overview Connected3

Overview

Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma is a phase 1/2 interventional study registered as NCT02704858 by Neonc Technologies, Inc., with 49 participants enrolled, started 2017-08-01 and due to reach its primary completion in 2026-11-30. Interventions recorded: Perillyl alcohol.

Setting

An Open-Label, Phase 1/2A Dose Escalation Study of Safety and Efficacy of NEO100 in Recurrent or Progressive Grade III or Grade IV Gliomas With IDH1 Mutation

Phase

Phase 1/2

Sponsor

Neonc Technologies, Inc.

Registry

Started

2017-08-01

Enrolled

49 enrolled

Connected

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Treatment
Safusidenib
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cancers

Astrocytoma, IDH-mutant (grades 2 to 4)Glioma & glioblastoma

companies

Neonc Technologies

Evidence strength16/100 · Preliminary

How much and what kind of evidence, not how big the benefit. Click for the breakdown.

Phase 1/2+8
49 enrolled+8
No structured primary endpoint0
Result: active0
No independent replication recorded0

Formula disclosed on the evidence page.

ProvenanceLast edited 2026-09-18 · Jude Gomila · Link 1,018 registry trials to cancer subtype pages by dri… · diff · file

Sources & links

ClinicalTrials.gov NCT02704858

Data

JSON ·

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Cancers

Glioma & glioblastoma
Astrocytoma, IDH-mutant (grades 2 to 4)

Companies

Neonc Technologies

Not yet reviewedNeeds expert (clinical) review. Review this page or see the review queue and roster.

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