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Reflexology is foot massage guided by a map of the body that has no anatomical basis. Small trials report short-lived relaxation and pain relief similar to any gentle foot massage; guidelines list it as an option for pain only with low confidence.
Reflexology applies pressure to zones on the feet or hands said to correspond to organs. The underlying map has no anatomical or physiological support, but the practice is essentially a structured foot massage and randomised trials in breast cancer report small short-term reductions in pain, anxiety and fatigue compared with usual care, without clear advantage over ordinary foot massage. The 2022 SIO-ASCO pain guideline says reflexology or acupressure may be offered for general cancer pain, a weak recommendation on low-certainty evidence; the SIO breast guideline grades it as an option for quality of life. It is safe with the same precautions as massage (neuropathy, foot wounds, deep vein thrombosis).
Any effect is best explained by the general relaxation and attention effects of touch rather than by the claimed organ correspondences.
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Four technology pages on OnCo cite this paper by its DOI; this record gives the citation a page of its own so a reader can follow it without leaving OnCo. Read the abstract above alongside the citing pages listed under Related; the record was created automatically from the Europe PMC entry and its figures have not been checked by hand.
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