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ZNF814 (Zinc finger protein 814) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Gastric & gastro-oesophageal junction cancer.
UniProt has no function text for B7Z6K7; HGNC names it "zinc finger protein 814".
IntOGen calls it a driver in 1 cohort (1 activating, 0 loss-of-function), covering Stomach Adenocarcinoma.
In plain words · ZNF814 (Zinc finger protein 814) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Gastric & gastro-oesophageal junction cancer.
ZNF814 (Zinc finger protein 814) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Gastric & gastro-oesophageal junction cancer.
UniProt has no function text for B7Z6K7; HGNC names it "zinc finger protein 814". Locus 19q13.43 (HGNC).
No product in this corpus aims at ZNF814 yet. Drugs fit a pocket that exists only in one shape of the mutant protein and hold it there, off.
First described 2004. Earliest sequence paper UniProt cites for the protein: Ota et al, Nat. Genet, 2004, "Complete sequencing and characterization of 21,243 full-length human cDNAs". Source.
Sources: HGNC HGNC:33258 (approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)); UniProt B7Z6K7 (protein name, function text, keywords and locations (REST API)); IntOGen ZNF814 (driver in 1 cohort (Act 1, LoF 0); Compendium_Cancer_Genes.tsv release 20240920, CC0 1.0)
UniProt has no function text for B7Z6K7; HGNC names it "zinc finger protein 814". Locus 19q13.43 (HGNC).
Query for this target: (TITLE:"ZNF814" OR ABSTRACT:"ZNF814" OR TITLE:"zinc finger protein 814" OR ABSTRACT:"zinc finger protein 814" OR TITLE:"Zinc finger protein 814" OR ABSTRACT:"Zinc finger protein 814") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about ZNF814, not a curated reading list.