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Discovered cancer stem cells, showing leukaemia is driven by a rare population of self-renewing cells.
John E. Dick is a Senior Scientist at the Princess Margaret Cancer Centre and Canada Research Chair in Stem Cell Biology. He is known for discovering cancer stem cells, identifying leukaemic stem cells in acute myeloid leukaemia between 1994 and 1997 and later pre-leukaemic haematopoietic stem cells, which defined the hierarchical model of cancer. His selected papers show that human AML is organised as a hierarchy originating from a primitive haematopoietic cell, and identify pre-leukaemic haematopoietic stem cells in acute leukaemia. A Gairdner and Keio Prize laureate, he continues to study leukaemia stem cells, haematopoiesis and pre-leukaemic clones.
Shares Princess Margaret Cancer Centre, Acute myeloid leukaemia.
Shares Cancer stem cell theory and phenotypic plasticity, Acute myeloid leukaemia.
Shares Theories of cancer: how the ideas connect, Acute myeloid leukaemia.
Shares Cancer stem cell theory and phenotypic plasticity, Acute myeloid leukaemia.
Shares Princess Margaret Cancer Centre, Cancer stem cell theory and phenotypic plasticity, Theories of cancer: how the ideas connect.
Shares Cancer stem cell theory and phenotypic plasticity, Acute myeloid leukaemia.
Shares Cancer stem cell theory and phenotypic plasticity, Theories of cancer: how the ideas connect, Acute myeloid leukaemia.
Shares Cancer stem cell theory and phenotypic plasticity, Acute myeloid leukaemia.