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Analysing 8,800 patients worldwide, the INRG task force built a pretreatment classification for neuroblastoma using stage, age, histology, MYCN, chromosome 11q and ploidy that sorts children into very low, low, intermediate and high-risk groups.
Analysis of 8,800 children with neuroblastoma diagnosed between 1990 and 2002 from international cooperative groups, defining sixteen pretreatment groups by INRG stage, age, histological category, grade of differentiation, MYCN status, 11q aberration and ploidy, assigned to four risk groups by five-year event-free survival.
Every neuroblastoma risk group on this site (very low, low, intermediate, high) is defined by the INRG system, which allows trials across continents to be compared.
Shares Low-risk neuroblastoma (INRG very low and low risk, including stage MS), Journal of Clinical Oncology.
Shares Intermediate-risk neuroblastoma, Journal of Clinical Oncology.
Shares Low-risk neuroblastoma (INRG very low and low risk, including stage MS), Intermediate-risk neuroblastoma, High-risk neuroblastoma.
Shares Low-risk neuroblastoma (INRG very low and low risk, including stage MS), Intermediate-risk neuroblastoma, High-risk neuroblastoma.
Shares Low-risk neuroblastoma (INRG very low and low risk, including stage MS), Intermediate-risk neuroblastoma, High-risk neuroblastoma.
Shares Low-risk neuroblastoma (INRG very low and low risk, including stage MS), Intermediate-risk neuroblastoma, High-risk neuroblastoma.
Shares Low-risk neuroblastoma (INRG very low and low risk, including stage MS), Intermediate-risk neuroblastoma, High-risk neuroblastoma.
Shares Intermediate-risk neuroblastoma, High-risk neuroblastoma.