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This consensus statement standardised how inflammatory breast cancer is diagnosed, with rapid onset of breast redness and swelling involving at least a third of the breast, and set out its trimodality treatment.
Consensus from an international expert panel defining the clinical diagnostic criteria for inflammatory breast cancer, recommended staging, the requirement for biopsy confirmation, and treatment with neoadjuvant systemic therapy followed by modified radical mastectomy and post-mastectomy radiotherapy, with HER2-directed therapy where appropriate.
The definition used in trials and clinics, and the insistence on systemic therapy first and mastectomy rather than breast conservation, come from this document.