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The eighth-edition melanoma staging system, derived from over 46,000 patients, refined thickness cut-offs and node categories and created the stage IIIA to IIID subgroups whose very different outlooks now guide adjuvant therapy decisions.
Description of the American Joint Committee on Cancer eighth-edition staging for melanoma, based on an international database of 46,000 patients, including changes to T1 subcategories, removal of mitotic rate from T1 staging, revised N categories incorporating microsatellites and in-transit disease, new stage III subgroups, and M1 subcategories with lactate dehydrogenase.
Stage IIB, IIC and III on this site's melanoma pages, and the recognition that stage IIIA has a better prognosis than stage IIB or IIC, come from this system.
Shares Stage IIB and IIC melanoma, Stage III melanoma (after surgery).
Shares Stage IIB and IIC melanoma, Stage III melanoma (after surgery).
Shares Stage IIB and IIC melanoma, Stage III melanoma (after surgery).
Shares Stage IIB and IIC melanoma, Stage III melanoma (after surgery).
Shares Stage IIB and IIC melanoma, Stage III melanoma (after surgery).
Shares Stage IIB and IIC melanoma, Stage III melanoma (after surgery).
Shares Stage IIB and IIC melanoma, Stage III melanoma (after surgery).