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Genes & Development
A Cold Spring Harbor molecular biology journal where much of the foundational work on oncogenes, tumour suppressors, senescence and cancer gene regulation was published.
Also called: Genes DevGenes and Development
Overview
Genes & Development (Genes Dev) is a molecular biology journal from Cold Spring Harbor Laboratory Press, founded in 1987, appearing twice a month and available on a hybrid model with articles free after six months. It covers molecular genetics, chromatin and transcription, cell cycle and development, with a strong cancer biology strand spanning p53, Myc, Ras signalling, senescence and epigenetic regulators, and much of the foundational work on oncogenes, tumour suppressors, senescence and cancer gene regulation was published here. Its readers are molecular and cell biologists. Within OnCo it is linked from the biographies of Leif Ellisen, Adrian Krainer and Justin Lathia, and a reader would use it for the foundational mechanism papers on oncogenes, tumour suppressors and senescence.
Publisher
Cold Spring Harbor Laboratory Press
Scope
basic cancer biology
Website
Access model
hybrid
Founded
1987
ISSN
0890-9369
Adrian R. Krainer
St. Giles Foundation Professor
RNA splicingAntisense oligonucleotidesSplicing in cancer
Adrian Krainer invented the antisense drug nusinersen and studies how splicing errors drive cancer.
Justin D. Lathia
Melvin H. Burkhardt Endowed Chair for Neuro-Oncology Clinical Research; Vice Chair, Cardiovascular and Metabolic Sciences
Glioblastoma stem cellsSex differences in cancerTumour microenvironment
Justin Lathia studies glioblastoma stem cells and why brain tumours differ between men and women.
Leif W. Ellisen
Program Director, Breast Medical Oncology
Breast cancer geneticsp53 family and p63Cancer predisposition
Runs breast medical oncology at MGH and studies the tumour-suppressor biology behind hereditary and triple-negative breast cancer.