The university where Tasuku Honjo discovered PD-1 and Shinya Yamanaka created iPS cells; its hospital leads Japanese immunotherapy and cell therapy research.
Kyoto University Hospital is the clinical arm of a university whose Graduate School of Medicine produced two Nobel prizes relevant to cancer: Tasuku Honjo's discovery of PD-1 (2018 Nobel), which led to nivolumab, and Shinya Yamanaka's induced pluripotent stem cells (2012 Nobel), now the basis of iPS-derived NK and T-cell products from the Center for iPS Cell Research and Application. The hospital runs Japan's largest early-phase immunotherapy programme with Ono Pharmaceutical partnerships, a leading haematology and transplant department, hepatobiliary and pancreatic surgery, and a core institution role in JCOG and WJOG trials. Its Institute for Advancement of Clinical and Translational Science supports investigator-initiated trials, and Kyoto's cancer research includes the Kyoto Prize-associated work on immune checkpoint biology.
From OpenAlex, oncology works in the last five years (2022 to 2026, current year in progress); counted on 2026-09-15.
Matched to Kyoto University Hospital, including child institutions. 251 works · 1,942 citations · 71% open access · 16% clinical trials · 1% reviews.
Hematologist who directs Kyoto University Hospital, one of Japan's leading academic medical centres.
He discovered the PD-1 molecule on T cells in 1992 and showed it acts as a brake on immune attack. Blocking it produced nivolumab and pembrolizumab, now used across dozens of cancers; Nobel Prize 2018.
Shares PD-L1, PD-1, Immune checkpoint inhibitors, Non-small-cell lung cancer.
Shares Japan Clinical Oncology Group (JCOG), Gastric & gastro-oesophageal junction cancer, Non-small-cell lung cancer.
Shares CAR-NK & CAR-macrophage, Allogeneic (off-the-shelf) cell therapy, Acute myeloid leukaemia.
Shares PD-L1, Nivolumab, PD-1, Immune checkpoint inhibitors.
Shares CAR-NK & CAR-macrophage, Allogeneic (off-the-shelf) cell therapy.
Shares PD-L1, Nivolumab, PD-1, Immune checkpoint inhibitors.