Scans find unexpected lumps in the adrenal, thyroid, pancreas and lung. Nobody knows how many matter. A national cohort following them for ten years would tell us whom to watch.
Scans find unexpected lumps in the adrenal, thyroid, pancreas and lung, and nobody knows how many matter, so this idea enrols every incidental finding flagged by structured radiology reporting into a national linked cohort followed for ten years. Incidentaloma guidelines rest on small retrospective series; natural history data is the missing evidence, and structured reporting makes capture feasible. The cohort would estimate cancer risk by lesion type, size and patient factors and allow follow-up recommendations to be pruned where risk is very low. The test is enrolment in a national health system with interim analyses at three and five years. Speculative in maturity, it addresses the bottlenecks Overdiagnosis and false alarms and Weak real-world evidence and registries.
Shares Overdiagnosis in cancer, Overdiagnosis and false alarms, MRI.
Shares Overdiagnosis in cancer, Overdiagnosis and false alarms, CT (computed tomography).
Shares Overdiagnosis in cancer, Overdiagnosis and false alarms, CT (computed tomography).
Shares Overdiagnosis in cancer, Overdiagnosis and false alarms.
Shares Overdiagnosis in cancer, Overdiagnosis and false alarms.
Shares Overdiagnosis in cancer, Overdiagnosis and false alarms.
Shares Overdiagnosis in cancer, Overdiagnosis and false alarms.
Shares Overdiagnosis in cancer, Overdiagnosis and false alarms.