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Instead of separate screening programmes for a few cancers, assess every adult's overall cancer risk and offer blood tests, imaging and preventive treatment tuned to that risk, all inside one system that learns.
Screening today covers a handful of cancers with organ-specific programmes and reaches a fraction of eligible people. Multi-cancer early detection blood tests (NHS-Galleri, PATHFINDER 2) and polygenic, exposure and imaging-based risk models make a unified approach conceivable: every adult over 40 receives a risk profile, a personalised detection schedule, and where indicated interception (chemoprevention, vaccines, risk-reducing procedures), with all results feeding a national learning system that recalibrates the models. Overdiagnosis is controlled through molecular indolence classifiers and surveillance-first protocols.
Shares FAPI PET as the workup for MCED positives, Whole-body MRI, Early detection of cancer, Positive predictive value (PPV).
Shares PATHFINDER 2, Galleri, NHS-Galleri, Positive predictive value (PPV).
Shares PATHFINDER 2, Galleri, NHS-Galleri, Stage shift.
Shares PATHFINDER 2, Galleri, NHS-Galleri, Positive predictive value (PPV).
Shares PATHFINDER 2, Galleri, NHS-Galleri, Positive predictive value (PPV).
Shares Early detection of cancer, Galleri, Positive predictive value (PPV), Multi-cancer early detection (MCED).
Shares PATHFINDER 2, Early detection of cancer, NHS-Galleri, Multi-cancer early detection (MCED).
Shares Early detection of cancer, Positive predictive value (PPV), Overdiagnosis and false alarms, The hardest cancers are found late.