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Once a proposal in a neglected cancer passes a quality bar, pick winners by lottery instead of by tiny differences in review scores, which mostly reflect fashion.
Reviewer scores in the middle of the distribution are nearly random and are known to favour established fields and safe applicants. For pancreatic, oesophageal, glioblastoma, sarcoma, mesothelioma and other neglected cancers, a funder would run a two-stage process: a rigorous pass/fail quality gate, then random selection among passes. This removes fashion bias, lowers the cost of applying and reviewing, and makes it easier to enter a new field.
Shares Funding follows fashion, not burden, Glioma & glioblastoma, Pancreatic ductal adenocarcinoma.
Shares Funding follows fashion, not burden, Oesophageal cancer, Sarcomas (soft tissue, bone, GIST).
Shares Mesothelioma, Oesophageal cancer, Sarcomas (soft tissue, bone, GIST).
Shares Funding follows fashion, not burden, Pancreatic ductal adenocarcinoma.
Shares Mesothelioma, Oesophageal cancer.
Shares Funding follows fashion, not burden, Sarcomas (soft tissue, bone, GIST).
Shares Mesothelioma, Oesophageal cancer.