Exact Sciences' entry into the leftover-cancer blood test market, launched in 2025 for bowel cancer follow-up.
Oncodetect launched in 2025 with initial validation in stage II-IV colorectal cancer, where the company reported that ctDNA positivity after surgery and during surveillance was strongly associated with recurrence, and Medicare coverage for colorectal surveillance followed. Exact Sciences has Cologuard's primary-care channel and the Oncotype DX oncology sales force behind it, which makes the test a commercial rather than technical challenge to Signatera. Broader indications and interventional trials are pending.
Whole-exome sequencing of tumour tissue designs a patient-specific panel of up to 200 variants tracked in plasma by targeted sequencing.
1.Oncodetect slips into a pocket on its target.
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Query for this drug: (TITLE:"Oncodetect" OR ABSTRACT:"Oncodetect") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Oncodetect, not a curated reading list.
Shares ctDNA MRD positivity (molecular residual disease after curative treatment), Signatera, Minimal / molecular residual disease (MRD), Circulating tumour DNA (ctDNA) and the tag test.
Shares ctDNA MRD positivity (molecular residual disease after curative treatment), Signatera, Minimal / molecular residual disease (MRD), Circulating tumour DNA (ctDNA) and the tag test.
Shares Exact Sciences (Abbott), Liquid biopsy (ctDNA) and the tag test.
Shares Circulating tumour DNA (ctDNA), Liquid biopsy (ctDNA) and the tag test.
Shares ctDNA MRD positivity (molecular residual disease after curative treatment), Minimal / molecular residual disease (MRD), MRD / molecular residual disease testing and the tag test.
Shares Exact Sciences (Abbott), Colorectal cancer and the tag test.
Shares Exact Sciences (Abbott), Colorectal cancer and the tag test.
Shares Circulating tumour DNA (ctDNA), Liquid biopsy (ctDNA) and the tag test.