Loading
SNAP25 (Synaptosomal-associated protein 25) is a gene. The public catalogues list it as a drug target, and an approved or late-stage drug is recorded against it. This dossier gathers the 0 products (0 approved), 0 trials, 0 pathways and 0 resistance routes in the corpus that involve it, with external identifiers so it can be joined to UniProt, ChEMBL, Open Targets and the rest of biology.
t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. Location: Cytoplasm, perinuclear region; Cell membrane; Synapse, synaptosome; Photoreceptor inner segment (UniProt). Locus 20p12.2 (HGNC).
No product in the corpus is aimed at this target yet.
No trial in the corpus names this target or one of its products.
No recorded escape route names this target.
No pathway diagram carries this target as a node.
No companion diagnostic in the registry measures this target.
No model entry for this target yet; check the cancer entries on the models page.
No open questions recorded for this target yet. Suggest one.
Query for this target: (TITLE:"SNAP25" OR ABSTRACT:"SNAP25" OR TITLE:"synaptosome associated protein 25" OR ABSTRACT:"synaptosome associated protein 25" OR TITLE:"Synaptosomal-associated protein 25" OR ABSTRACT:"Synaptosomal-associated protein 25" OR TITLE:"SNAP-25" OR ABSTRACT:"SNAP-25" OR TITLE:"RIC-4" OR ABSTRACT:"RIC-4" OR TITLE:"RIC4" OR ABSTRACT:"RIC4") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about SNAP25, not a curated reading list.
The dossier as machine-readable JSON, at /api/v1/dossiers/snap25.json: identifiers from HGNC, Ensembl, UniProt and ChEMBL, products with status, trials, pathways, hotspots, open questions and assays. The full entity record is in the open API at /api/v1/entities/snap25.json. Licence CC BY-NC 4.0.