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SLC24A5 (Sodium/potassium/calcium exchanger 5) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Skin cancer. This dossier gathers the 0 products (0 approved), 0 trials, 0 pathways and 0 resistance routes in the corpus that involve it, with external identifiers so it can be joined to UniProt, ChEMBL, Open Targets and the rest of biology.
Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+). Involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-calcium exchanger in melanocytes. Location: Golgi apparatus, trans-Golgi network membrane; Melanosome (UniProt). Locus 15q21.1 (HGNC).
No product in the corpus is aimed at this target yet.
No trial in the corpus names this target or one of its products.
No recorded escape route names this target.
No pathway diagram carries this target as a node.
No companion diagnostic in the registry measures this target.
No model entry for this target yet; check the cancer entries on the models page.
No open questions recorded for this target yet. Suggest one.
Query for this target: (TITLE:"SLC24A5" OR ABSTRACT:"SLC24A5" OR TITLE:"solute carrier family 24 member 5" OR ABSTRACT:"solute carrier family 24 member 5" OR TITLE:"Sodium/potassium/calcium exchanger 5" OR ABSTRACT:"Sodium/potassium/calcium exchanger 5" OR TITLE:"OCA6" OR ABSTRACT:"OCA6" OR TITLE:"NCKX5" OR ABSTRACT:"NCKX5") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about SLC24A5, not a curated reading list.
The dossier as machine-readable JSON, at /api/v1/dossiers/slc24a5.json: identifiers from HGNC, Ensembl, UniProt and ChEMBL, products with status, trials, pathways, hotspots, open questions and assays. The full entity record is in the open API at /api/v1/entities/slc24a5.json. Licence CC BY-NC 4.0.