Loading
PTPN3 (Tyrosine-protein phosphatase non-receptor type 3) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Pancreatic ductal adenocarcinoma. This dossier gathers the 0 products (0 approved), 0 trials, 0 pathways and 0 resistance routes in the corpus that involve it, with external identifiers so it can be joined to UniProt, ChEMBL, Open Targets and the rest of biology.
May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity. Location: Cell membrane; Cytoplasm, cytoskeleton (UniProt). Locus 9q31.3 (HGNC).
No product in the corpus is aimed at this target yet.
No trial in the corpus names this target or one of its products.
No recorded escape route names this target.
No pathway diagram carries this target as a node.
No companion diagnostic in the registry measures this target.
No model entry for this target yet; check the cancer entries on the models page.
No open questions recorded for this target yet. Suggest one.
Query for this target: (TITLE:"PTPN3" OR ABSTRACT:"PTPN3" OR TITLE:"protein tyrosine phosphatase non-receptor type 3" OR ABSTRACT:"protein tyrosine phosphatase non-receptor type 3" OR TITLE:"Tyrosine-protein phosphatase non-receptor type 3" OR ABSTRACT:"Tyrosine-protein phosphatase non-receptor type 3" OR TITLE:"PTPH1" OR ABSTRACT:"PTPH1") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about PTPN3, not a curated reading list.
The dossier as machine-readable JSON, at /api/v1/dossiers/ptpn3.json: identifiers from HGNC, Ensembl, UniProt and ChEMBL, products with status, trials, pathways, hotspots, open questions and assays. The full entity record is in the open API at /api/v1/entities/ptpn3.json. Licence CC BY-NC 4.0.