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NUTM1 (NUT family member 1) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a tumour suppressor and a fusion partner, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Skin cancer, Oesophageal cancer, Ovarian cancer and 4 more. This dossier gathers the 0 products (0 approved), 0 trials, 0 pathways and 0 resistance routes in the corpus that involve it, with external identifiers so it can be joined to UniProt, ChEMBL, Open Targets and the rest of biology.
Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites. Location: Cytoplasm; Nucleus (UniProt). Locus 15q14 (HGNC).
No product in the corpus is aimed at this target yet.
No trial in the corpus names this target or one of its products.
No recorded escape route names this target.
No pathway diagram carries this target as a node.
No companion diagnostic in the registry measures this target.
No model entry for this target yet; check the cancer entries on the models page.
No open questions recorded for this target yet. Suggest one.
Query for this target: (TITLE:"NUTM1" OR ABSTRACT:"NUTM1" OR TITLE:"NUT midline carcinoma family member 1" OR ABSTRACT:"NUT midline carcinoma family member 1" OR TITLE:"NUT family member 1" OR ABSTRACT:"NUT family member 1" OR TITLE:"DKFZp434O192" OR ABSTRACT:"DKFZp434O192" OR TITLE:"FAM22H" OR ABSTRACT:"FAM22H" OR TITLE:"C15orf55" OR ABSTRACT:"C15orf55") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about NUTM1, not a curated reading list.
The dossier as machine-readable JSON, at /api/v1/dossiers/nutm1.json: identifiers from HGNC, Ensembl, UniProt and ChEMBL, products with status, trials, pathways, hotspots, open questions and assays. The full entity record is in the open API at /api/v1/entities/nutm1.json. Licence CC BY-NC 4.0.