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SERB Pharmaceuticals
SERB is a European specialty company focused on emergency and rescue medicines; in oncology it markets glucarpidase (Voraxaze) for toxic methotrexate levels and uridine triacetate (Vistogard) for fluorouracil overdose in Europe.
Overview
SERB Pharmaceuticals, based in Paris, is a European specialty company focused on emergency and rescue medicines; in oncology it markets glucarpidase, sold as Voraxaze, for toxic methotrexate levels and uridine triacetate, sold as Vistogard, for fluorouracil overdose in Europe. It acquired BTG's specialty pharmaceuticals business in 2021, adding Voraxaze, CroFab and DigiFab, and distributes antidotes and rescue therapies used in oncology supportive care. OnCo links it to glucarpidase, uridine triacetate and telotristat ethyl. Whether rarely used antidotes remain stocked and affordable when a single company holds them is the question that matters for the patients who suddenly need them. Glucarpidase has its own page.
Headquarters
Paris, FR
Scorecard
All companies#158of 1244 companies, score 37
- approved products +18
- modalities +6
- regions +2
- registry trials +11
3 approved, 0 in phase 3, 0 earlier, 0 targets, 33 registry studies. Formula on the scorecards page.
Type
Website
ApprovedRecombinant bacterial enzyme (rescue agent)
Glucarpidase · Voraxaze
Glucarpidase (Voraxaze) is a single emergency injection that chops up methotrexate in the blood when a patient's kidneys have failed to clear a high dose, preventing potentially fatal toxicity.
ApprovedOral tryptophan hydroxylase inhibitor
Telotristat ethyl · Xermelo
Telotristat ethyl (Xermelo) is a tablet that cuts the serotonin that neuroendocrine tumours pour out, easing the constant diarrhoea of carcinoid syndrome when somatostatin analogue injections are not enough.
ApprovedPyrimidine analogue antidote (oral)
Uridine triacetate · Vistogard
Uridine triacetate (Vistogard) is an oral antidote for fluorouracil or capecitabine overdose, or for dangerously early severe toxicity from these drugs, and must be started within four days of the chemotherapy.
Similar pages
drugs
ApprovedRecombinant bacterial enzyme (rescue agent)
Glucarpidase · Voraxaze
ApprovedOral tryptophan hydroxylase inhibitor
Telotristat ethyl · Xermelo
ApprovedPyrimidine analogue antidote (oral)
Uridine triacetate · Vistogard