Prestige Biopharma is a Singapore-based antibody company, listed in Korea, that makes biosimilars and is developing PBP1510, a first-in-class antibody against the pancreatic cancer protein PAUF.
Prestige Biopharma develops biosimilars, including trastuzumab (Tuznue) and bevacizumab candidates, and novel antibodies. PBP1510 (ulenistamab) neutralises pancreatic adenocarcinoma up-regulated factor (PAUF), a secreted protein that drives tumour growth and immune evasion; it has orphan designations in the United States and Europe and is in a phase 1/2a trial with gemcitabine in advanced pancreatic cancer. The company also develops PBP1710 against CTHRC1.
PBP1510 is a monoclonal antibody from Prestige Biopharma Limited, in registered phase 2 trials for pancreatic ductal adenocarcinoma.