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medac
medac is a German family-owned pharmaceutical company whose alkylating agent treosulfan, long used in Europe, was approved by the FDA in 2025 as conditioning treatment before stem cell transplantation in acute myeloid leukaemia and myelodysplastic syndromes.
Also called: medac GmbHmedac Pharma
Overview
medac GmbH, based in Wedel near Hamburg, is a privately held German company specialising in haematology, oncology, urology and autoimmune disease. Its alkylating agent treosulfan, approved in Europe for decades and marketed there as Trecondi for transplant conditioning, received FDA approval in January 2025 (Grafapex) with fludarabine as a preparative regimen before allogeneic haematopoietic stem cell transplantation in adults and children with acute myeloid leukaemia or myelodysplastic syndromes. Company facts are from the official website and FDA approval records.
Headquarters
Wedel, DE
Scorecard
All companies#211of 1244 companies, score 25
- approved products +6
- modalities +2
- regions +3
- registry trials +14
1 approved, 0 in phase 3, 0 earlier, 0 targets, 51 registry studies. Formula on the scorecards page.
Type
Stage
Large private
Website
ApprovedAlkylating conditioning agent (busulfan analogue)
Treosulfan · Grafapex
A conditioning chemotherapy given before donor stem-cell transplant in AML and MDS; it was long used in Europe and reached the US in 2025.
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cancers
fronts
drugs
ApprovedAlkylating conditioning agent (busulfan analogue)
Treosulfan · Grafapex