Kartos Therapeutics is a United States-based biotechnology company running 3 late-stage cancer trials of KRT-232 and Ruxolitinib in myeloproliferative neoplasms, endometrial cancer and diffuse large B-cell lymphoma.
Kartos Therapeutics, based in Redwood City, the United States, is a biotechnology company. Kartos Therapeutics is a clinical-stage biopharmaceutical company developing targeted therapeutics for patients with cancer. On ClinicalTrials.gov it is the lead sponsor of 3 recruiting or active phase 2 and phase 3 interventional cancer trials (1 in phase 3), testing KRT-232 and Ruxolitinib in myeloproliferative neoplasms, endometrial cancer, diffuse large B-cell lymphoma, chronic lymphocytic leukaemia and hodgkin lymphoma. The largest, NCT05797831 (Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer), plans to enrol 268 participants. Sponsor and trial facts are from the ClinicalTrials.gov registry; company facts are from the official website.
KRT-232 is an experimental small-molecule drug from Kartos Therapeutics in phase 2 trials for myeloproliferative neoplasms, diffuse large B-cell lymphoma and chronic lymphocytic leukaemia, aimed at MDM2 and TP53.
Shares Myeloproliferative neoplasms (PV, ET, myelofibrosis), Chronic lymphocytic leukaemia, Hodgkin lymphoma, Diffuse large B-cell lymphoma.
Shares Myeloproliferative neoplasms (PV, ET, myelofibrosis), Chronic lymphocytic leukaemia, Hodgkin lymphoma, Diffuse large B-cell lymphoma.
Shares Myeloproliferative neoplasms (PV, ET, myelofibrosis), Chronic lymphocytic leukaemia, Hodgkin lymphoma, Diffuse large B-cell lymphoma.
Shares Myeloproliferative neoplasms (PV, ET, myelofibrosis), Chronic lymphocytic leukaemia.
Shares Myeloproliferative neoplasms (PV, ET, myelofibrosis), Endometrial cancer.
Shares Myeloproliferative neoplasms (PV, ET, myelofibrosis), Endometrial cancer.
Shares Myeloproliferative neoplasms (PV, ET, myelofibrosis), Endometrial cancer.
Shares Myeloproliferative neoplasms (PV, ET, myelofibrosis), Endometrial cancer.