JW Therapeutics, a Juno and WuXi AppTec joint venture, made relma-cel, the first CAR-T developed and manufactured in China to be approved.
Relmacabtagene autoleucel (Carteyva) approved 2021 for large B-cell lymphoma and 2022 for follicular lymphoma; pipeline in mantle cell lymphoma, leukaemia and autoimmune disease. Its commercial struggle (list price around CN¥ 1.29 million, not NRDL-listed, provincial supplementary insurance filling some of the gap) is the case study for how China pays for cell therapy.
Relma-cel was the first CAR-T therapy developed and made in China to be approved, for large B-cell lymphoma that has come back after two treatments.
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