Genelux is a United States-based biotechnology company running 2 late-stage cancer trials of olvimulogene nanivacirepvec and Olvimulogene nanivacirepvec in ovarian cancer and non-small-cell lung cancer.
Genelux, based in Westlake Village, CA, the United States, is a biotechnology company. Genelux is a biopharmaceutical company developing oncolytic immunotherapies based on a modified vaccinia virus platform. On ClinicalTrials.gov it is the lead sponsor of 2 recruiting or active phase 2 and phase 3 interventional cancer trials (1 in phase 3), testing olvimulogene nanivacirepvec and Olvimulogene nanivacirepvec in ovarian cancer and non-small-cell lung cancer. The largest, NCT05281471 (Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)), plans to enrol 186 participants. Sponsor and trial facts are from the ClinicalTrials.gov registry; company facts are from the official website.
Olvimulogene nanivacirepvec is an experimental oncolytic virus from Genelux in phase 3 trials for ovarian cancer and non-small-cell lung cancer, with its target not yet stated publicly.