CSL is the Australian plasma-products and vaccines group whose CSL Behring arm makes immunoglobulins and clotting factors used in supportive cancer care, and which has sponsored phase 3 trials in cancer settings.
CSL Limited, listed in Melbourne since 1994 and descended from the Commonwealth Serum Laboratories, is one of the world's largest plasma-derived medicines makers through CSL Behring, based in King of Prussia, Pennsylvania, alongside its Seqirus vaccines business. In oncology its products are supportive: immunoglobulin replacement for patients with blood cancers or after CAR-T therapy, and haemostatic agents. ClinicalTrials.gov lists CSL Behring as lead sponsor of phase 3 trials in cancer-related settings.
Intravenous immunoglobulin is pooled antibody from many blood donors. People with chronic lymphocytic leukaemia or myeloma whose own antibody levels have collapsed, and who keep getting bacterial infections despite antibiotics, receive it as replacement.