AOP Health is a Vienna rare-disease company that brought ropeginterferon alfa-2b (Besremi) to the European market for polycythaemia vera and runs trials in myeloproliferative neoplasms and other rare conditions.
AOP Health (formerly AOP Orphan Pharmaceuticals) is a privately held Austrian company focused on rare diseases and intensive care medicine. In cancer it licensed ropeginterferon alfa-2b from PharmaEssentia for Europe and other territories, obtained European approval for polycythaemia vera in 2019 under the name Besremi, and sponsors phase 3 trials of the drug in myeloproliferative neoplasms. It appears on OnCo as a lead sponsor of phase 3 cancer trials on ClinicalTrials.gov.
Ropeginterferon alfa-2b is a long-acting interferon for polycythaemia vera that, unlike hydroxyurea, can shrink the mutant clone over years.