All of Us Research Program

The All of Us Research Program is America's answer to UK Biobank, built with diversity as its organising principle. It is a US cohort targeting one million participants with genomes, electronic health records and surveys, with an emphasis on groups under-represented in research. More than 250,000 whole genomes have been released, and linkage to health records enables models of cancer risk and outcome across ancestries. The programme is maintained by the NIH and is accessed through the registered tier of the Researcher Workbench. It is filed as a data collection alongside comparable population resources such as UK Biobank, and it matters to this corpus because ancestry-diverse cohorts are what allow risk and outcome models to be checked beyond European populations.