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Cancers
Recurrent or metastatic cervical cancer
What changed

Recurrent or metastatic cervical cancer

What changed: Recurrent or metastatic cervical cancer

Cancer page →

Every dated change on the records linked to Recurrent or metastatic cervical cancer, newest first: approvals and regulatory steps on its medicines, trials that reported, guideline versions, milestones, and when this page itself was checked. Dates come from the records; none is inferred. Orientation, not medical advice.

Overview Types and stages Symptoms and diagnosis Treatment Trials and papers Biology and targets Countries and centres Decisions and support Pipeline and open problems Data

Regulatory1Trial result7Milestone6This record1On Edge

FollowWatch this cancer and Saved shows what changed since you last looked.Follow by feed

September 2026 · 1

2026-09-17This recordRecurrent or metastatic cervical cancer
Facts on this page last checked
When this page itself was last checked or edited.

2024 · 2

2024Trial resultCOMPASSION-16 / AK104-303
COMPASSION-16 / AK104-303 reported
OS HR 0.
2024MilestoneTisotumab vedotin
Tisotumab vedotin full approval; COMPASSION-16 positive for cadonilimab in China
A milestone in how this cancer is treated.

2023 · 4

2023Trial resultBEATcc / ENGOT-Cx10 / GOG-3030
BEATcc / ENGOT-Cx10 / GOG-3030 reported
OS 32.
2023Trial resultDESTINY-PanTumor02
DESTINY-PanTumor02 reported
Endometrial ORR 57.
2023Trial resultinnovaTV 301 / ENGOT-cx12 / GOG-3057
innovaTV 301 / ENGOT-cx12 / GOG-3057 reported
OS 11.
2023MilestoneinnovaTV 301 / ENGOT-cx12 / GOG-3057
innovaTV 301 and BEATcc positive
A milestone in how this cancer is treated.

September 2021 · 1

2021-09-20RegulatoryTisotumab vedotin
Tisotumab vedotin: accelerated approval (US)
Accelerated approval, recurrent or metastatic cervical cancer after chemotherapy (innovaTV 204)

2021 · 4

2021Trial resultEMPOWER-Cervical 1 / GOG-3016 / ENGOT-cx9
EMPOWER-Cervical 1 / GOG-3016 / ENGOT-cx9 reported
OS 12.
2021Trial resultKEYNOTE-826
KEYNOTE-826 reported
OS 26.
2021MilestoneKEYNOTE-826
KEYNOTE-826: pembrolizumab with chemotherapy extends median survival to 26.4 months
A milestone in how this cancer is treated.
2021MilestoneTisotumab vedotin
Tisotumab vedotin accelerated approval; EMPOWER-Cervical 1 positive for cemiplimab
A milestone in how this cancer is treated.

2020 · 1

2020Trial resultCheckMate 358
CheckMate 358 reported
Neoadjuvant nivolumab produced pathological complete responses in a substantial share of resectable Merkel cell carcinomas, with durable responses; nivolumab also showed activity in recurrent cervical cancer.

2014 · 1

2014MilestoneBevacizumab
GOG-0240: bevacizumab extends survival in advanced cervical cancer
A milestone in how this cancer is treated.

2009 · 1

2009MilestoneCisplatin
GOG-0204: cisplatin-paclitaxel confirmed as the reference doublet
A milestone in how this cancer is treated.