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The decisions you may face, the aids that walk through them, the warnings on record, the first sixty days and the questions to ask.
One section per setting: the options named, what each is for, the trials behind them, the recorded trade-offs and the questions to ask.
A swollen painful calf, or sudden breathlessness with chest pain; the tamoxifen boxed warning covers pulmonary embolism and stroke.
Breast Cancer Now lists headache, sickness and vomiting especially on waking, weakness or numbness down one side of the body, unsteadiness or loss of balance, seizures, difficulty with speech, vision problems, and changes in behaviour, mood or memory among the signs that breast cancer may have spread to the brain. A seizure, a sudden severe headache or new one-sided weakness is 999 whatever the cause.
The NHS says to call 999 or go to A and E if you have cellulitis with a very high temperature or you feel hot, cold or shivery, a fast heartbeat or fast breathing, purple patches on the skin which may be less obvious on brown or black skin, feeling dizzy or faint, confusion or disorientation, cold, clammy or pale skin, or unresponsiveness. These are symptoms of serious complications, which can be life threatening.
Fainting, dizziness or an irregular heartbeat; QT prolongation is a labelled warning and ECGs are checked in the first cycles.
Breathing very fast; confused, slurred speech or not making sense; blue, pale or blotchy skin, lips or tongue; a very high or very low temperature, feeling hot or cold to the touch, or shivery; a rash that does not fade when pressed: the NHS says call 999 or go to A and E, and do not drive yourself, ask someone to drive you or call 999.
A swollen painful calf, or sudden breathlessness with chest pain; venous thromboembolism including pulmonary embolism is a labelled warning.
See all on the product pages:AbemaciclibBone metastases and skeletal-related eventsBrain metastases (intracranial disease)CamizestrantCompression, decongestive therapy and exercise for lymphoedemaElacestrantFebrile neutropeniaGiredestrantGoserelin / leuprolide (ovarian function suppression)ImlunestrantLetrozole (and other aromatase inhibitors)Lymphadenectomy (lymph node dissection)Lymphoedema after breast cancer treatmentNeutropenic sepsis: the temperature rule and the 999 signsOlaparibPalbociclibRibociclibSeroma after breast surgerySurvivorship care and late-effects surveillanceTalazoparibTamoxifen·Printable cards in the navigator
What the next twelve months look like, phase by phase, with the decision points.
Newly diagnosed? Read the first 60 days with HR-positive / HER2-negative breast cancer, then print the one-page appointment sheet with room for the answers.
Print this page for your appointment (your browser's print command). These prompts are for discussion; your clinical team knows your case.