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| Cancers | Other tags | ||||
|---|---|---|---|---|---|
AMICO: aerobic or resistance exercise to improve outcome in metastatic colorectal cancer NCT04754672 CHALLENGE showed exercise improves survival after curative treatment for colon cancer. AMICO asks the next question, in advanced disease, with chemotherapy dose modification and progression-free survival as its primary endpoints, and uses an adaptive design to drop an ineffective exercise prescription early. | Colorectal cancer | none | rejuvenation, survivorship, open-problem | ||
Mahesh K. B. Parmar Director, MRC Clinical Trials Unit at UCL; Professor of Medical Statistics and Epidemiology · University College London Hospitals / UCL Cancer Institute Statistician who invented the multi-arm multi-stage design behind STAMPEDE, letting one trial test many treatments at once. | Prostate cancer | none | biostatistics, platform-trials |