Loading
ZNF750 (Zinc finger protein 750) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Oesophageal cancer, Oesophageal and junctional adenocarcinoma and Non-small-cell lung cancer. This dossier gathers the 0 products (0 approved), 0 trials, 0 pathways and 0 resistance routes in the corpus that involve it, with external identifiers so it can be joined to UniProt, ChEMBL, Open Targets and the rest of biology.
Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression. Location: Nucleus (UniProt). Locus 17q25.3 (HGNC).
No product in the corpus is aimed at this target yet.
No trial in the corpus names this target or one of its products.
No recorded escape route names this target.
No pathway diagram carries this target as a node.
No companion diagnostic in the registry measures this target.
No model entry for this target yet; check the cancer entries on the models page.
No open questions recorded for this target yet. Suggest one.
Query for this target: (TITLE:"ZNF750" OR ABSTRACT:"ZNF750" OR TITLE:"zinc finger protein 750" OR ABSTRACT:"zinc finger protein 750" OR TITLE:"Zinc finger protein 750" OR ABSTRACT:"Zinc finger protein 750" OR TITLE:"FLJ13841" OR ABSTRACT:"FLJ13841" OR TITLE:"Zfp750" OR ABSTRACT:"Zfp750") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about ZNF750, not a curated reading list.
The dossier as machine-readable JSON, at /api/v1/dossiers/znf750.json: identifiers from HGNC, Ensembl, UniProt and ChEMBL, products with status, trials, pathways, hotspots, open questions and assays. The full entity record is in the open API at /api/v1/entities/znf750.json. Licence CC BY-NC 4.0.