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SLC6A3 (Sodium-dependent dopamine transporter) is a gene. The public catalogues list it as a drug target, and an approved or late-stage drug is recorded against it. This dossier gathers the 0 products (0 approved), 0 trials, 0 pathways and 0 resistance routes in the corpus that involve it, with external identifiers so it can be joined to UniProt, ChEMBL, Open Targets and the rest of biology.
Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signalling. Location: Cell membrane; Cell projection, neuron projection; Cell projection, axon (UniProt). Locus 5p15.33 (HGNC).
No product in the corpus is aimed at this target yet.
No trial in the corpus names this target or one of its products.
No recorded escape route names this target.
No pathway diagram carries this target as a node.
No companion diagnostic in the registry measures this target.
No model entry for this target yet; check the cancer entries on the models page.
No open questions recorded for this target yet. Suggest one.
Query for this target: (TITLE:"SLC6A3" OR ABSTRACT:"SLC6A3" OR TITLE:"solute carrier family 6 member 3" OR ABSTRACT:"solute carrier family 6 member 3" OR TITLE:"Sodium-dependent dopamine transporter" OR ABSTRACT:"Sodium-dependent dopamine transporter" OR TITLE:"DAT1" OR ABSTRACT:"DAT1") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about SLC6A3, not a curated reading list.
The dossier as machine-readable JSON, at /api/v1/dossiers/slc6a3.json: identifiers from HGNC, Ensembl, UniProt and ChEMBL, products with status, trials, pathways, hotspots, open questions and assays. The full entity record is in the open API at /api/v1/entities/slc6a3.json. Licence CC BY-NC 4.0.